The following is from The Vaccine Reaction.
A 2023 analysis published by researchers from Kaiser Permanente and the U.S. Centers for Disease Control and Prevention (CDC) in the journal Pediatrics compared vaccine adverse outcomes following administration of Pfizer/BioNTech’s Comirnaty messenger RNA (mRNA) Covid-19 shot and Moderna/NIAID’s Spikevax mRNA Covid-19 shot among recipients under five years old for a period of 1-21 days post-vaccination, compared to outcomes among those vaccinated 22-42 days post-vaccination.
The authors reported that 104 children under the age of five suffered seizures after receiving an mRNA Covid shot.
Although the study authors said that safety surveillance of more than 245,000 mRNA Covid shot doses over a period of nine months did not detect a safety signal for any outcome during the 21 days after vaccination, the data did show many adverse outcomes in absolute terms.
Researchers leading the study used a process known as Rapid Cycle Analysis (RCA) to examine adverse vaccine outcomes of mRNA Covid shots on children under the age of five.
RCA methods used in the CDC’s Vaccine Safety Datalink (VSD) were developed to conduct population-based monitoring of potential outcomes associated with a vaccine in near real-time by examining outcome rates in recent vaccine recipients during risk intervals in relation to rates during comparison intervals.
Any associations between a vaccine and adverse outcomes produced by this approach are considered statistical signals that indicate the need for further investigation into the safety of a vaccine.
The first period of 1-21 days, known as the “primary risk interval,” is believed to be the time-period that vaccinated people are more likely to experience adverse events. The period from 22-42 days is known as a comparison interval.
Even though it is an assumption that adverse events that occur more than 21 days after vaccination are not associated with the vaccine received, according to William Schaffner, MD, a professor of preventative medicine at Vanderbilt University, said:
The idea for the events that occur in the latter period is that ‘it’s too late for them to be associated with a vaccine.“
The analysis examined specific events that fit one or more of 23 specified outcomes, including seizures, myocarditis, appendicitis, Bell’s palsy, encephalitis, etc. following mRNA Covid shots.
The analysis examined data available from June 18, 2022 to Mar. 18, 2023.
135,005 doses of Comirnaty were given to children six months to four years of age and 112,006 doses of Spikevax were given to children six months to five years of age in the VSD population. (Continued…)
Link to article here.
